Or click on the first letter of the article:

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Ichthyosis vulgaris

Ichthyosis vulgaris: A genetic skin disease that is characterized by scaly (fishlike) areas of skin. The first scaly skin problems usually appear after 3 months of age. The palms and soles are often affected. Areas that tend to be spared include the axillae (the armpits), the antecubital fossa (the inside area at the bend of the elbow) and the popliteal fossa (behind the knee).

A significant proportion of people with this disease have asthma , eczema or hay fever .

The gene responsible ichthyosis vulargaris has been mapped to chromosome band 1q21. The product of this gene is a substance called filaggrin (abbreviated FLG) which may act as the "keratin matrix protein" in cells of the stratum corneum, one of the layers of the skin.

Also known as ichthyosis simplex.

Last updated on 07/03/2008

© 1996-2004 MedicineNet, Inc. All rights reserved.

Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. You should carefully read all product packaging. If you have or suspect you have a medical problem, promptly contact your professional healthcare provider.

Statements and information regarding dietary supplements have not been evaluated or approved by the Food and Drug Administration. Please consult your healthcare provider before beginning any course of supplementation or treatment.